SCHEMBL505735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL505519	0.93	RAB9A (0.45)	RAB9ASMN1; SMN2KDM4EMAPTCASP3
	SCHEMBL505690	0.88	GRM5 (0.44)	RAB9ASMN1; SMN2KDM4EMAPTPDE10A
	SCHEMBL505070	0.87	GRM5 (0.43)	RAB9ASMN1; SMN2GRM5NPC1GPR119
	SCHEMBL505498	0.85	GRM5 (0.53)	RAB9ASMN1; SMN2KDM4EMAPTGRM5
	SCHEMBL10251605	0.84	GRM5 (0.40)	RAB9ASMN1; SMN2MAPTGRM5NPC1
	SCHEMBL505267	0.82	GRM5 (0.44)	RAB9ASMN1; SMN2KDM4EMAPTGRM5
	SCHEMBL505881	0.81	SMN1; SMN2 (0.47)	RAB9ASMN1; SMN2KDM4EMAPTCASP3
	SCHEMBL505117	0.80	GRM5 (0.46)	RAB9ASMN1; SMN2KDM4EMAPTPDE10A
	SCHEMBL10251519	0.80	GRM5 (0.43)	GRM5GPR119ADRA1A
	SCHEMBL505041	0.79	GRM5 (0.45)	RAB9ASMN1; SMN2PDE10AGRM5NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.