SCHEMBL505267

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL505519	0.90	RAB9A (0.45)	GRM5KDM4EALDH1A1HPGDRAB9A
	SCHEMBL10250324	0.89	GRM5 (0.46)	GRM5KDM4EALDH1A1HPGDRAB9A
	SCHEMBL505666	0.88	GRM5 (0.56)	GRM5KDM4EALDH1A1HPGDRAB9A
	SCHEMBL505982	0.87	GRM5 (0.46)	GRM5KDM4EALDH1A1HPGDACHE
	SCHEMBL505373	0.85	GRM5 (0.44)	GRM5KDM4EALDH1A1HSD17B10NPC1
	SCHEMBL7879696	0.83	NPC1 (0.35)	KDM4EALDH1A1HPGDRAB9AMAPT
	SCHEMBL505117	0.83	GRM5 (0.46)	GRM5KDM4EALDH1A1HPGDRAB9A
	SCHEMBL7881575	0.83	MAPT (0.36)	KDM4EALDH1A1HPGDRAB9AMAPT
	SCHEMBL505735	0.82	RAB9A (0.45)	GRM5KDM4EALDH1A1HPGDRAB9A
	SCHEMBL505041	0.82	GRM5 (0.45)	GRM5ALDH1A1HPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.