SCHEMBL5057366

SCHEMBL5057366

[CH]=Cc1[c]cc2cc3cc4ccccc4cc3cc2c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5050123 1.00 ALDH1A1 (0.34) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL5057486 1.00 ALDH1A1 (0.34) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL5748269 0.80 ALDH1A1 (0.34) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL5749036 0.71 CYP2A6 (0.35) ALDH1A1CASP1CASP7HIF1AHSD17B10
SCHEMBL16289240 0.71 ALDH1A1 (0.33) ALDH1A1CYP3A4ALOX15HSD17B10TDP1
SCHEMBL2255305 0.68 ALDH1A1 (0.48) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL2700600 0.68 CYP2A6 (0.39) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL1557253 0.68 CYP2A6 (0.39) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL4838243 0.68 CYP2A6 (0.39) ALDH1A1CYP3A4ALOX15CASP1CASP7
SCHEMBL871457 0.68 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US claimed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO claimed
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US disclosed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO disclosed