Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748269 | 0.92 | ALDH1A1 (0.34) | CYP2A6ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL16289240 | 0.78 | ALDH1A1 (0.33) | CYP2A6ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL17288828 | 0.74 | CA1 (0.31) | CYP2A6CA1CA2 | |
| SCHEMBL5057486 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TDP1CASP1CASP7HIF1A | |
| SCHEMBL5050123 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TDP1CASP1CASP7HIF1A | |
| SCHEMBL5057366 | 0.71 | ALDH1A1 (0.34) | ALDH1A1TDP1CASP1CASP7HIF1A | |
| SCHEMBL6163163 | 0.69 | CYP2A6 (0.37) | CYP2A6ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9883837 | 0.67 | ERN1 (0.48) | CYP2A6ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL6630769 | 0.67 | TSHR (0.37) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL2002417 | 0.67 | PTGS2 (0.41) | CYP2A6MEN1KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |