⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115406 | 0.78 | — | — | |
| SCHEMBL27990990 | 0.78 | — | — | |
| SCHEMBL8143562 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL9066678 | 0.70 | ALDH1A1 (0.54) | — | |
| SCHEMBL65852 | 0.70 | — | — | |
| SCHEMBL1479028 | 0.70 | — | — | |
| Water SCHEMBL7924253 | 0.70 | ALDH1A1 (0.30) | — | |
| SCHEMBL11874539 | 0.70 | ALDH1A1 (0.30) | — | |
| SCHEMBL993677 | 0.70 | — | — | |
| SCHEMBL28239112 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | claimed |
| EP-2393771-A1 | Method for the synthesis of chiral alpha-aryl propionic acid derivatives | DSM IP Assets B.V. (NL) | 2011-12-14 | — | — | EP | claimed |
| WO-2010089343-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2010-08-12 | — | — | WO | claimed |
| EP-1969939-A2 | Nematicidal compositions | Devgen NV (BE) | 2008-09-17 | — | — | EP | claimed |
| US-20080146445-A1 | Nematicidal Compositions | DEVGEN NV (BE) | 2008-06-19 | — | — | US | claimed |
| US-5237099-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2-alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1993-08-17 | — | — | US | claimed |
| EP-0228564-B1 | NOVEL INSECTICIDAL DIACYLHYDRAZINE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1992-01-29 | — | — | EP | claimed |
| US-4814349-A | Insecticidal substituted and unsubstituted benzoic acid 1-alkyl, 2 alkyl and 2-cycloalkylhydrazides | AMERICAN CYANAMID COMPANY (US) | 1989-03-21 | — | — | US | claimed |
| EP-0093977-B1 | 2,5-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1987-08-05 | — | — | EP | claimed |
| EP-0228564-A2 | Novel insecticidal diacylhydrazine compounds | AMERICAN CYANAMID COMPANY (US) | 1987-07-15 | — | — | EP | claimed |
| US-4533676-A | 2,5-Dihalogenobenzoyl-(thio)urea insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | claimed |
| EP-0093976-A1 | 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides | BAYER AG (DE) | 1983-11-16 | — | — | EP | claimed |
| JP-7330507-A | — | — | None | — | — | JP | disclosed |
| EP-2460408-A1 | Nematicidal compositions | deVGen N.V. (BE) | 2012-06-06 | — | — | EP | disclosed |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | disclosed |
| EP-2393771-A1 | Method for the synthesis of chiral alpha-aryl propionic acid derivatives | DSM IP Assets B.V. (NL) | 2011-12-14 | — | — | EP | disclosed |
| EP-0072529-A1 | Sulfur-substituted phenoxypyridines having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| US-4371537-A | Sulfur-substituted phenoxypyridines having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4349568-A | Sulfur-substituted diphenyl ethers having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |