⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7562031 | 0.84 | FFAR3 (0.33) | — | |
| SCHEMBL115406 | 0.74 | — | — | |
| SCHEMBL2465562 | 0.72 | — | — | |
| SCHEMBL181476 | 0.72 | — | — | |
| SCHEMBL666082 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL505749 | 0.70 | — | — | |
| SCHEMBL28815631 | 0.69 | — | — | |
| SCHEMBL27990990 | 0.67 | — | — | |
| SCHEMBL129262 | 0.67 | — | — | |
| SCHEMBL15700155 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158374-A1 | Pyrazolopyridine Derivatives and Uses thereof | NOVARTIS AG (CH) | 2024-05-16 | — | — | US | disclosed |
| EP-4308562-A1 | PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2024015924-A2 | HYBRID OLIGONUCLEOTIDES | ENTRADA THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-20240000890-A1 | NEURAL REGENERATION WITH SYNTHETIC PROTEIN ADMINISTRATION | Retinal Solutions, LLC (US) | 2024-01-04 | — | — | US | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| CN-116802182-A | Pyrazolopyridine derivatives and uses thereof | 诺华股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230126239-A1 | NORRIN REGULATION OF PLASMALEMMA VESICLE-ASSOCIATED PROTEIN AND USE TO TREAT MACULAR DEGENERATION | Retinal Solutions, LLC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230108325-A1 | Pyrazolopyridine Derivatives and Uses thereof | NOVARTIS AG (CH) | 2023-04-06 | — | — | US | disclosed |
| EP-4117708-A1 | NORRIN REGULATION OF PLASMALEMMA VESICLE-ASSOCIATED PROTEIN AND USE TO TREAT MACULAR DEGENERATION | Retinal Solutions, LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| WO-2021183407-A1 | NORRIN REGULATION OF PLASMALEMMA VESICLE-ASSOCIATED PROTEIN AND USE TO TREAT MACULAR DEGENERATION | Retinal Solutions, LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| US-7262268-B2 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates | CUBIST PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20060223983-A1 | Lipopeptide stereoisomers, methods for preparing same and useful intermediates | CUBIST PHARMACEUTICALS, INC. | 2006-10-05 | — | — | US | disclosed |
| EP-1423137-A4 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARM INC (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1423137-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | Cubist Pharmaceuticals, Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030096948-A1 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates | ADOLOR CORPORATION | 2003-05-22 | — | — | US | disclosed |
| WO-2003017924-A2 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARMACEUTICALS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| EP-0842195-A1 | PEPTIDE INHIBITORS OF FIBRONECTINE | ZENECA LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997002289-A1 | PEPTIDE INHIBITORS OF FIBRONECTINE | ZENECA LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |
| EP-0285562-B1 | SYNTHETIC RESIN | CIBA-GEIGY AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| EP-0285562-A2 | Synthetic resin | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |