SCHEMBL505784

SCHEMBL505784

CC(C)(C)C([SiH2]O)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030604 0.61
SCHEMBL1611766 0.61
SCHEMBL205358 0.56
SCHEMBL2865136 0.56
SCHEMBL3117161 0.56
Ammonia Solution, Strong SCHEMBL490795 0.53
SCHEMBL10197407 0.53 TSHR (0.41)
SCHEMBL10197405 0.53 TSHR (0.41)
SCHEMBL2164167 0.53 TSHR (0.41)
SCHEMBL1051866 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120029226-A1 METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES DSM IP ASSETS B.V. (NL) 2012-02-02 US claimed
EP-3268353-B1 PYRAZOLYL DERIVATIVES AS PEST CONTROL AGENTS BAYER ANIMAL HEALTH GMBH (DE) 2020-09-09 EP disclosed
EP-3157913-B1 PYRAZOLYL TRIAZOLYL PYRIDINES AS PESTICIDE BAYER ANIMAL HEALTH GMBH (DE) 2019-04-17 EP disclosed
EP-3089972-B1 NOVEL PYRAZOLE HETEROARYLAMIDES AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2018-05-16 EP disclosed
EP-3268353-A1 PYRAZOLYL-DERIVATIVES AS PEST CONTROL AGENTS Bayer Animal Health GmbH (DE) 2018-01-17 EP disclosed
EP-2953942-B1 HALOGEN-SUBSTITUTED PYRAZOLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2017-10-25 EP disclosed
EP-2794573-B1 NOVEL INSECTICIDAL AROMATIC AMIDES BAYER IP GMBH (DE) 2017-08-30 EP disclosed
EP-2964631-B1 HALOGEN-SUBSTITUTED N-[3-(1H-PYRAZOL-4-YL)PHENYLMETHYL]-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PESTICIDES FOR USE IN CROP PROTECTION IN VETERINARY MEDICINE AND IN MATERIAL PROTECTION BAYER ANIMAL HEALTH GMBH (DE) 2017-08-30 EP disclosed
EP-3157913-A1 PYRAZOLYL-TRIAZOLYL-PYRIDINES AS PEST-CONTROL AGENTS Bayer Animal Health GmbH (DE) 2017-04-26 EP disclosed
EP-3126353-A1 NOVEL 3-[(PYRAZOL-5-YL)-HETEROARYL]-BENZAMIDE DERIVATIVES AND USE THEREOF AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2017-02-08 EP disclosed
US-5532369-A NUCLEOTIDE INHIBITORS OF PHOSPHODIESTERASE SANKYO COMPANY, LIMITED (JP) 1996-07-02 US disclosed
US-5498819-A INHIBITORS OF PHOSPHODIESTERASE AS NEUROTROPIC AGENTS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS, ANTICARCINOGENIC AGENTS AND ANTIDIABETIC AGENTS SANKYO COMPANY, LIMITED (JP) 1996-03-12 US disclosed
EP-0318060-B1 Griseolic acid derivatives, their preparation and their use SANKYO CO (JP) 1995-10-25 EP disclosed
EP-0319050-B1 Griseolic acid derivatives, their preparation and their use SANKYO CO (JP) 1995-04-12 EP disclosed
EP-0251827-B1 NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-09-15 EP disclosed
US-4891363-A PLATELET ACTIVATING FACTOR ANTAGONISTS SANKYO COMPANY LIMITED (JP) 1990-01-02 US disclosed
EP-0214708-B1 GRISEOLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE SANKYO COMPANY LIMITED (JP) 1989-12-13 EP disclosed
EP-0319050-A2 Griseolic acid derivatives, their preparation and their use SANKYO COMPANY LIMITED (JP) 1989-06-07 EP disclosed
EP-0318060-A2 Griseolic acid derivatives, their preparation and their use Sankyo Company Limited (JP) 1989-05-31 EP disclosed
EP-0251827-A2 New cyclic ether derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-01-07 EP disclosed