Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197405 | 1.00 | TSHR (0.41) | TSHRALDH1A1LMNASLC6A2SLC6A4 | |
| SCHEMBL19164023 | 1.00 | TSHR (0.41) | TSHRALDH1A1LMNASLC6A2SLC6A4 | |
| SCHEMBL888915 | 0.82 | — | — | |
| SCHEMBL888909 | 0.82 | — | — | |
| SCHEMBL19164010 | 0.82 | TSHR (0.37) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2526677 | 0.82 | TSHR (0.37) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2744382 | 0.82 | — | — | |
| SCHEMBL2508340 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL17286791 | 0.79 | — | — | |
| SCHEMBL4631767 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102470361-B | Reactive systems | ELANTAS GMBH (DE) | 2015-12-16 | — | — | CN | claimed |
| US-9056927-B2 | Reactive systems | ELANTAS GMBH (DE) | 2015-06-16 | — | — | US | claimed |
| EP-2454017-B1 | REACTIVE SYSTEMS | ELANTAS GMBH (DE) | 2015-03-18 | — | — | EP | claimed |
| CN-104387368-A | Method for preparing dexilant | SICHUAN HAIRONG PHARMACEUTICAL CO LTD YANGTZE RIVER PHARMACEUTICAL GROUP | 2015-03-04 | — | — | CN | claimed |
| US-20120190787-A1 | REACTIVE SYSTEMS | ELANTAS GMBH (DE) | 2012-07-26 | — | — | US | claimed |
| CN-102470361-A | Reactive system | ELANTAS GMBH | 2012-05-23 | — | — | CN | claimed |
| CN-113045385-B | Method for synthesizing aliphatic pinacol | 广东工业大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-113045385-A | Method for synthesizing aliphatic pinacol | 广东工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-109750371-A | Cross embroidery superbright light polyester filament and preparation method thereof | 江苏恒力化纤股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109750373-A | High-strength activates polyester industrial yarn and preparation method thereof | 江苏恒力化纤股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109750372-A | Wool-Like polyester filament and preparation method thereof | 江苏恒力化纤股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109735979-A | The preparation method of the different dye-uptake low elastic polyester filament of iso-fineness | 江苏恒力化纤股份有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109735918-A | Imitative viscose glue polyester filament and preparation method thereof | 江苏恒力化纤股份有限公司 | 2019-05-10 | — | — | CN | disclosed |
| US-20120122844-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | NOVARTIS AG (CH) | 2012-05-17 | — | — | US | disclosed |
| US-20100305131-A1 | Substituted Aminopropionic Derivatives as Neprilysin inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| US-20100305131-A1 | Substituted Aminopropionic Derivatives as Neprilysin inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| US-7416868-B2 | Polyene polyketides, processes for their production and their use as a pharmaceutical | THALLION PHARMACEUTICALS, INC. (CA) | 2008-08-26 | — | — | US | disclosed |
| US-7375088-B2 | Polyene polyketides, processes for their production and their use as a pharmaceutical | THALLION PHARMACEUTICALS INC. (CA) | 2008-05-20 | — | — | US | disclosed |
| US-20070275436-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | ECOPIA BIOSCIENCES, INC. | 2007-11-29 | — | — | US | disclosed |
| US-7300921-B2 | Polyene polyketides and methods of production | ECOPIA BIOSCIENCES, INC. (CA) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305131-A1 | Substituted Aminopropionic Derivatives as Neprilysin inhibitors | MME, AGTR1, REN | TSHR 3209/4885ALDH1A1 852/4885LMNA 635/4885 |
| US-20070275436-A1 | Polyene polyketides, processes for their production and their use as a pharmaceutical | IPMK, PANK3, PANK1 | TSHR 4148/4885ALDH1A1 4091/4885LMNA 1798/4885 |
| US-20120122844-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | REN, SERPINB1, MME | TSHR 1328/4885ALDH1A1 2474/4885LMNA 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.