Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 19/20 | 0.53 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.52 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388761 | 0.97 | NPY1R (0.51) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL4652031 | 0.91 | NPY1R (0.48) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL1388313 | 0.91 | NPY1R (0.44) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL4650707 | 0.89 | NPY1R (0.43) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL4651777 | 0.88 | CNR1 (0.48) | NPY1RNPY5RNPY4R | |
| SCHEMBL4651114 | 0.87 | NPY1R (0.45) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8122927 | 0.86 | NPY1R (0.42) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8528706 | 0.86 | TMPRSS11D (0.43) | NPY1RNPY5RNPY4R | |
| SCHEMBL4653106 | 0.85 | TP53 (0.44) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL8653899 | 0.85 | NPY1R (0.52) | NPY1RNPFFR1NPFFR2NPY5RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213803-A1 | ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR | OREGON HEALTH & SCIENCE UNIVERSITY | 2008-09-04 | — | — | US | disclosed |
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |