Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 14/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750543 | 0.86 | NPY1R (0.57) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL5057899 | 0.86 | NPY1R (0.53) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL1388313 | 0.85 | NPY1R (0.44) | NPY1RTLR2NPY4RNPY5RNPFFR1 | |
| SCHEMBL4651777 | 0.84 | CNR1 (0.48) | NPY1RTLR2NPY4RNPY5R | |
| SCHEMBL8528706 | 0.84 | TMPRSS11D (0.43) | NPY1RTLR2NPY4RNPY5RPOLB | |
| SCHEMBL1388761 | 0.83 | NPY1R (0.51) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL4651114 | 0.81 | NPY1R (0.45) | NPY1RTLR2NPY4RNPY5RNPFFR1 | |
| SCHEMBL8612664 | 0.80 | CNR1 (0.44) | NPY1RNPY5RMEN1KMT2A | |
| SCHEMBL4650707 | 0.80 | NPY1R (0.43) | NPY1RTLR2NPY4RNPY5RNPFFR1 | |
| SCHEMBL4651789 | 0.79 | TRPV1 (0.43) | NPY1RMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |