Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251635 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL15776693 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL5548988 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL25419509 | 0.86 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL25001507 | 0.84 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL3569051 | 0.84 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL24027122 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL1127697 | 0.84 | PPARG (0.58) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL17921387 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A | |
| SCHEMBL14446963 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124270-A1 | Compounds Useful as Metal Chelators | BRACCO IMAGING S.P.A. (IT) | 2008-05-29 | — | — | US | disclosed |
| US-20080124270-A1 | Compounds Useful as Metal Chelators | BRACCO IMAGING S.P.A. (IT) | 2008-05-29 | — | — | US | disclosed |
| US-20080124270-A1 | Compounds Useful as Metal Chelators | BRACCO IMAGING S.P.A. (IT) | 2008-05-29 | — | — | US | disclosed |
| EP-1699466-A2 | NEW COMPOUNDS USEFUL AS METAL CHELATORS | Bracco Imaging, S.P.A. (IT) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005062828-A2 | NEW COMPOUNDS USEFUL AS METAL CHELATORS | BRACCO IMAGING S.P.A. (IT) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124270-A1 | Compounds Useful as Metal Chelators | PAICS, PHOSPHO1, PPIP5K2 | ALDH1A1 4035/4885SMN1; SMN2 3701/4885MAPK1 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.