SCHEMBL5058573

SCHEMBL5058573

CCO[Si](C)(C)CC(C)OCC1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063191 0.86 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188407 0.86 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL229592 0.86 SMN1; SMN2 (0.34) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL28906298 0.84 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL4924940 0.83 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5597326 0.81 SMN1; SMN2 (0.31) SMN1; SMN2ALDH1A1
SCHEMBL11766827 0.81 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1TDP1
SCHEMBL5031053 0.77 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5598823 0.77 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL188483 0.77 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080022886-A1 COATING COMPOSITIONS EXHIBITING CORROSION RESISTANCE PROPERTIES, RELATED COATED SUBSTRATES, AND METHODS PPG INDUSTRIES OHIO, INC. (US) 2008-01-31 US disclosed