SCHEMBL5031053

SCHEMBL5031053

CCO[Si](C)(C)CC(C)COCC1CO1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026325 0.87 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3804296 0.87 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5028998 0.83 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28292331 0.82 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL4751088 0.79 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL4751377 0.79 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL49463 0.78 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5378987 0.78 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL4347990 0.77 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5058573 0.77 SMN1; SMN2 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10941323-B2 Composite of metal and resin ADVANCED TECHNOLOGIES, INC. (JP) 2021-03-09 US disclosed
US-20200377767-A1 COMPOSITE OF METAL AND RESIN ADVANCED TECHNOLOGIES, INC. (JP) 2020-12-03 US disclosed
CN-110997314-B Composite material of metal and resin 株式会社新技术研究所 2020-10-09 CN disclosed
EP-3663084-A1 COMPOSITE OF METAL AND RESIN Advanced Technologies, Inc. (JP) 2020-06-10 EP disclosed
CN-110997314-A Composite material of metal and resin 株式会社新技术研究所 2020-04-10 CN disclosed
US-20080214744-A1 Coating composition, making method, and coated article SHIN-ETSU CHEMICAL CO., LTD. 2008-09-04 US disclosed
EP-1947124-A2 Coating compositions, their preparation and use and articles and materials coated therewith Shin-Etsu Chemical Co., Ltd. (JP) 2008-07-23 EP disclosed