Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 4/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058728 | 1.00 | INSR (0.48) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7719119 | 0.92 | CHRM2 (0.54) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5460996 | 0.90 | LMNA (0.43) | MAPK1TDP1LMNAKDM4ECYP2C19 | |
| SCHEMBL15065449 | 0.90 | LMNA (0.43) | MAPK1TDP1LMNAKDM4ECYP2C19 | |
| SCHEMBL5712574 | 0.90 | CHRM2 (0.55) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10340840 | 0.90 | LMNA (0.43) | MAPK1TDP1LMNAKDM4ECYP2C19 | |
| SCHEMBL5712573 | 0.90 | CHRM2 (0.55) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1832514 | 0.90 | CHRM2 (0.55) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2604957 | 0.88 | CHRM2 (0.57) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15871096 | 0.88 | CYP1A2 (0.42) | MEN1ALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449578-B1 | substituted phenanthroline compounds with high two photon absorption cross sections; [3,8-Bis-{4-[2-(4-tert-butylsulfanyl-phenylvinyl]-phenyl}-[1,10] phenanthroline | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-11-11 | — | — | US | disclosed |