SCHEMBL5059644

SCHEMBL5059644

CC(C)(N)COC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
TSHR P16473 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
SLC13A5 Q86YT5 9/20 0.36
KDM4E B2RXH2 5/20 0.34
LMNA P02545 3/20 0.34
MAPT P10636 2/20 0.34
ALOX15 P16050 1/20 0.34
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC13A2 Q13183 1/20 0.30
SLC13A3 Q8WWT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28654759 0.86 ALDH1A1 (0.56) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL424422 0.86 ALDH1A1 (0.56) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL429567 0.85 ALDH1A1 (0.50) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL28489420 0.81 ALDH1A1 (0.50) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL31538120 0.81 ALDH1A1 (0.65) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL424483 0.79 ALDH1A1 (0.52) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Citric Acid SCHEMBL238240 0.79 ALDH1A1 (0.75) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL426446 0.79 ALDH1A1 (0.47) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL30163090 0.79 ALDH1A1 (0.56) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL9320048 0.79 ALDH1A1 (0.56) ALDH1A1HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008068062-A1 DISPERSION CONTAINING TITANIUM DIOXIDE EVONIK DEGUSSA GMBH (DE) 2008-06-12 WO claimed
WO-2008068062-A1 DISPERSION CONTAINING TITANIUM DIOXIDE EVONIK DEGUSSA GMBH (DE) 2008-06-12 WO disclosed