Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424422 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL5059644 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL28654759 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL424424 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL536596 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL429569 | 0.82 | ALDH1A1 (0.68) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL426446 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL28489420 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL31069901 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL424483 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020906-A1 | ANTIPERSPIRANT SPRAYS WITH ESTER OILS | HENKEL AG & CO. KGAA (DE) | 2012-01-26 | — | — | US | claimed |
| US-20170157025-A1 | TEXTILE FRIENDLY ANTIPERSPIRANT COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2017-06-08 | — | — | US | disclosed |
| US-8828367-B2 | Water-free antiperspirant non-aerosols in which active substances are more readily released | HENKEL AG & CO. KGAA (DE) | 2014-09-09 | — | — | US | disclosed |
| US-8603445-B2 | Water-free antiperspirant sprays in which active substances are more readily released | HENKEL AG & CO. KGAA (DE) | 2013-12-10 | — | — | US | disclosed |
| US-20120177589-A1 | WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED | HENKEL AG & CO. KGAA (DE) | 2012-07-12 | — | — | US | disclosed |
| US-20120171143-A1 | WATER-FREE ANTIPERSPIRANT SPRAYS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED | HENKEL AG & CO. KGAA (DE) | 2012-07-05 | — | — | US | disclosed |
| US-20120020906-A1 | ANTIPERSPIRANT SPRAYS WITH ESTER OILS | HENKEL AG & CO. KGAA (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020906-A1 | ANTIPERSPIRANT SPRAYS WITH ESTER OILS | CUTA, NAPEPLD, LIPE | ALDH1A1 1032/4885HMGCR 359/4885CHRM1 1805/4885 |
| US-20120177589-A1 | WATER-FREE ANTIPERSPIRANT NON-AEROSOLS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED | SIGMAR1, POLR1C, CUTA | ALDH1A1 2601/4885HMGCR 3199/4885CHRM1 559/4885 |
| US-20120171143-A1 | WATER-FREE ANTIPERSPIRANT SPRAYS IN WHICH ACTIVE SUBSTANCES ARE MORE READILY RELEASED | POLR1C, CUTA, PHOSPHO1 | ALDH1A1 1827/4885HMGCR 1373/4885CHRM1 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.