Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 5/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430142 | 0.85 | GSR (0.53) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL17982113 | 0.85 | GSR (0.53) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL5499007 | 0.85 | GSR (0.61) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL5495401 | 0.83 | GSR (0.59) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL19088201 | 0.79 | GSR (0.55) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL7294153 | 0.78 | GNAI3 (0.54) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL29989156 | 0.76 | GSR (0.57) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL5491543 | 0.76 | GNAI3 (0.64) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL4647979 | 0.76 | GNAI3 (0.64) | GNAI3GNAO1GNAI1DPP7DPP8 | |
| SCHEMBL4647986 | 0.76 | GNAI3 (0.64) | GNAI3GNAO1GNAI1DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080081343-A1 | Differential labeling for quantitative analysis of complex protein mixtures | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-03 | — | — | US | disclosed |
| US-7166436-B2 | Differential labeling for quantitative analysis of complex protein mixtures | SYNGENTA PARTICIPATIONS, AG (CH) | 2007-01-23 | — | — | US | disclosed |
| EP-1428019-A4 | SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-26 | — | — | EP | disclosed |
| US-20060004525-A1 | System and method of determining proteomic differences | SYNGENTA PARTICIPATIONS AG | 2006-01-05 | — | — | US | disclosed |
| US-6969757-B2 | Differential labeling for quantitative analysis of complex protein mixtures | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-29 | — | — | US | disclosed |
| WO-2002059144-A9 | DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES | SYNGENTA PARTICIPATIONS AG (US) | 2004-08-12 | — | — | WO | disclosed |
| EP-1428019-A2 | SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES | Syngenta Participations AG (CH) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003006951-A9 | SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-05-13 | — | — | WO | disclosed |
| US-20030087329-A1 | Differential labeling for quantitative analysis of complex protein mixtures | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-08 | — | — | US | disclosed |
| US-20030082522-A1 | Differential labeling for quantitative analysis of complex protein mixtures | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-01 | — | — | US | disclosed |
| US-20030068825-A1 | System and method of determining proteomic differences | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2003006951-A2 | SYSTEM AND METHOD OF DETERMINING PROTEOMIC DIFFERENCES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-01-23 | — | — | WO | disclosed |
| WO-2002059144-A2 | DIFFERENTIAL LABELING FOR QUANTITATIVE ANALYSIS OF COMPLEX PROTEIN MIXTURES | SYNGENTA PARTICIPATION AG (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087329-A1 | Differential labeling for quantitative analysis of complex protein mixtures | RPS27A, PSMG3, MRTO4 | GSR 3105/4885GNAI3 863/4885GNAO1 1030/4885 |
| US-20030082522-A1 | Differential labeling for quantitative analysis of complex protein mixtures | RPS27A, PSMG3, MRTO4 | GSR 3105/4885GNAI3 863/4885GNAO1 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.