Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338849 | 1.00 | SLC6A2 (0.60) | SLC6A2SLC6A4ALOX15EPHX2POLB | |
| SCHEMBL5053711 | 1.00 | SLC6A2 (0.60) | SLC6A2SLC6A4ALOX15EPHX2POLB | |
| SCHEMBL5060790 | 1.00 | SLC6A2 (0.60) | SLC6A2SLC6A4ALOX15EPHX2POLB | |
| SCHEMBL5053732 | 0.99 | SLC6A2 (0.61) | SLC6A2SLC6A4ALOX15EPHX2POLB | |
| SCHEMBL5053698 | 0.96 | EPHX2 (0.58) | SLC6A2SLC6A4ALOX15EPHX2POLB | |
| SCHEMBL5053658 | 0.92 | HTR1A (0.56) | SLC6A2SLC6A4EPHX2MAPTMAPK1 | |
| SCHEMBL5060794 | 0.92 | HTR1A (0.56) | SLC6A2SLC6A4EPHX2MAPTMAPK1 | |
| SCHEMBL5053727 | 0.92 | HTR1A (0.56) | SLC6A2SLC6A4EPHX2MAPTMAPK1 | |
| SCHEMBL5053729 | 0.92 | HTR1A (0.56) | SLC6A2SLC6A4EPHX2MAPTMAPK1 | |
| SCHEMBL12797500 | 0.91 | DRD2 (0.52) | SLC6A2SLC6A4ALOX15EPHX2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897764-B2 | Thiourea derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-03-01 | — | — | US | disclosed |
| US-7897764-B2 | Thiourea derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-03-01 | — | — | US | disclosed |
| US-20080306090-A1 | THIOUREA DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-11 | — | — | US | disclosed |
| US-20080306090-A1 | THIOUREA DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306090-A1 | THIOUREA DERIVATIVES | EIF2AK2, IFNAR1, TPMT | SLC6A2 2714/4885SLC6A4 2442/4885ALOX15 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.