Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014224 | 0.80 | RECQL (0.83) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL9197789 | 0.79 | RECQL (0.81) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL5009469 | 0.79 | RECQL (0.81) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL9374155 | 0.76 | RECQL (0.76) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL15597475 | 0.75 | SMN1; SMN2 (1.00) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL13720543 | 0.74 | SMN1; SMN2 (0.74) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL9207026 | 0.73 | ALDH1A1 (0.67) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL11170511 | 0.73 | ALDH1A1 (0.67) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL11170337 | 0.73 | ALDH1A1 (0.74) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL9200706 | 0.72 | AKR1B1 (0.73) | RECQLALDH1A1SMN1; SMN2L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |