Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | PARP1 | P09874 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | HTR2B | P41595 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.66 |
| ▸ | DRD5 | P21918 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060800 | 1.00 | HRH1 (0.85) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL1649764 | 0.92 | HRH1 (1.00) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL29359369 | 0.92 | HRH1 (1.00) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL4669 | 0.92 | HRH1 (1.00) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL4668 | 0.92 | HRH1 (1.00) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL29517420 | 0.92 | HRH1 (1.00) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL694414 | 0.91 | HRH1 (0.98) | HRH1LMNAPARP1KCNH2HTR2B | |
| Olopatadine SCHEMBL122589 | 0.91 | HRH1 (0.98) | HRH1LMNAPARP1KCNH2ALDH1A1 | |
| Olopatadine SCHEMBL23213 | 0.91 | HRH1 (0.98) | HRH1LMNAPARP1KCNH2ALDH1A1 | |
| Olopatadine SCHEMBL5324205 | 0.91 | HRH1 (0.98) | HRH1LMNAPARP1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | ALCON MANUFACTURING LTD. (US) | 2008-06-12 | — | — | US | claimed |
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | ALCON MANUFACTURING LTD. (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139531-A1 | USE OF CONNECTIVE TISSUE MAST CELL STABILIZERS TO FACILITATE OCULAR SURFACE RE-EPITHELIZATION AND WOUND REPAIR | CMA1, LTK, KIT | HRH1 35/4885LMNA 3550/4885PARP1 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.