Sugi Predict

Sugi Predict / Compounds / SCHEMBL5060829

SCHEMBL5060829

SCHEMBL5060829

O=COc1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.47
▸ RAB9A P51151 5/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ MAPK1 P28482 4/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ ELANE P08246 1/20 0.47
▸ TP53 P04637 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ CDC25B P30305 1/20 0.46
▸ BCL2 P10415 1/20 0.45
▸ MCL1 Q07820 1/20 0.45
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ LMNA P02545 3/20 0.43
▸ PLA2G1B P04054 3/20 0.43
▸ ATG4B Q9Y4P1 3/20 0.43
▸ MAPT P10636 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28193890 0.88 MCL1 (0.39) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL10489419 0.79 MEN1 (0.55) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL2608111 0.77 TDP1 (0.43) ALDH1A1TDP1MEN1KMT2AL3MBTL1
SCHEMBL29199299 0.77 NPC1 (0.43) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9563396 0.77 ALDH1A1 (0.49) NPC1RAB9AALDH1A1SMN1; SMN2CYP3A4
SCHEMBL12553374 0.76 TTR (0.56) ALDH1A1TDP1MEN1KMT2ACDC25B
SCHEMBL17718223 0.76 TTR (0.56) ALDH1A1TDP1MEN1KMT2ACDC25B
2-Methoxyanthraquinone SCHEMBL222927 0.76 PTPN1 (0.60) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL2267225 0.74 MAOA (0.62) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL4645032 0.74 PTPN1 (0.58) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111977621-B Production method of light-driven high-purity nitrous oxide 福建农林大学 2022-10-14 — — CN claimed
US-20250243606-A1 ANTIBACTERIAL AND ANTIVIRAL FABRICS UNIV CALIFORNIA (US) 2025-07-31 — — US disclosed
US-12270127-B2 Antibacterial and antiviral fabrics THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-08 — — US disclosed
CN-111977621-B Production method of light-driven high-purity nitrous oxide 福建农林大学 2022-10-14 — — CN disclosed
US-20220112629-A1 ANTIBACTERIAL AND ANTIVIRAL FABRICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-04-14 — — US disclosed
CN-112876495-A Parthenolide derivative, pharmaceutical composition thereof, preparation method and application thereof 中国医学科学院药物研究所 2021-06-01 — — CN disclosed
CN-111977621-A Production method of light-driven high-purity nitrous oxide 福建农林大学 2020-11-24 — — CN disclosed
CN-107078047-B Low temperature adhesive resin for die bonding 国际商业机器公司 2020-04-21 — — CN disclosed
CN-107434284-A A kind of molten wadding thing of clay for carbon tetrachloride processing, preparation method and applications 徐州工程学院 2017-12-05 — — CN disclosed
US-20130240763-A1 APPARATUS AND METHODS FOR REDUCING SOILING OF RADIO-OPAQUE SHIELDS BLOXR CORPORATION (US) 2013-09-19 — — US disclosed
US-20080302674-A1 Probe Unit, Apparatus for Identifying Nucleotide Region and Method of Identifying Nucleotide Region KYOTO UNIVERSITY (JP) 2008-12-11 — — US disclosed
EP-1830183-A1 PROBE UNIT, APPARATUS FOR IDENTIFYING NUCLEOTIDE REGION AND METHOD OF IDENTIFYING NUCLEOTIDE REGION Kyoto University (JP) 2007-09-05 — — EP disclosed