Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723317 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL1702480 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL1930571 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL9069200 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL21333932 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL31140049 | 0.87 | ALDH1A1 (0.89) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL1014433 | 0.86 | ALDH1A1 (0.86) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL31087985 | 0.84 | ALDH1A1 (0.49) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL649467 | 0.84 | ALDH1A1 (0.49) | ALDH1A1PRSS1PRSS2PRSS3KDM4E | |
| SCHEMBL27673461 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080050398-A1 | Composition Comprising Beta-Defensin 2 | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080050398-A1 | Composition Comprising Beta-Defensin 2 | DLK1, DSG1, DBNL | ALDH1A1 2395/4885PRSS1 1703/4885PRSS2 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.