Roxifiban

Roxifiban

SCHEMBL50632

C1=NOCC1.CCCCOC(=O)N[C@@H](CNC(=O)C[C@H]1CC(c2ccc(C(=N)N)cc2)=NO1)C(=O)OC

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.86
ITGA2B P08514 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Roxifiban SCHEMBL24336949 0.93 ITGB3 (1.00) ITGB3ITGA2B
Roxifiban SCHEMBL344302 0.93 ITGB3 (1.00) ITGB3ITGA2B
Roxifiban SCHEMBL919675 0.91 ITGB3 (0.95) ITGB3ITGA2B
SCHEMBL7213400 0.87 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL7220986 0.84 ITGB3 (0.83) ITGB3ITGA2B
SCHEMBL7413714 0.82 ITGB3 (0.80) ITGB3ITGA2B
SCHEMBL7407564 0.82 ITGB3 (0.80) ITGB3ITGA2B
SCHEMBL7214664 0.80 ITGB3 (0.76) ITGB3ITGA2B
SCHEMBL7217243 0.80 ITGB3 (0.76) ITGB3ITGA2B
SCHEMBL7214752 0.80 ITGB3 (0.76) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927203-B2 Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant BIOVEC TRANSFUSION, LLC (US) 2015-01-06 US disclosed
US-8697347-B2 Composition for preserving platelets and method of using the same BIOVEC TRANSFUSION, LLC (US) 2014-04-15 US disclosed
US-8329389-B2 Composition containing short-to-ultrashort GPIIb/IIIa and factor Xa inhibitors and platelets BIOVEC TRANSFUSION, LLC (US) 2012-12-11 US disclosed
US-8232044-B2 Method of extending the shelf life of platelets using a composition comprising a short-to-ultrashort antiplatelet agent and anticoagulant and an oxygen carrier BIOVEC TRANSFUSION, LLC (US) 2012-07-31 US disclosed
US-8142992-B2 Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier BIOVEC TRANSFUSION, LLC (US) 2012-03-27 US disclosed
US-20120058558-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME BIOVEC TRANSFUSION, LLC (US) 2012-03-08 US disclosed
US-8129103-B2 Use of a platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with an oxygen carrier BIOVEC TRANSFUSION, LLC (US) 2012-03-06 US disclosed
US-8129104-B2 Platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant with hemoglobin BIOVEC TRANSFUSION, LLC (US) 2012-03-06 US disclosed
WO-2011136791-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING AND STORING THE SAME BIOVEC TRANSFUSION, LLC (US) 2011-11-03 WO disclosed
US-20110223579-A1 Composition for Preserving Platelets and Method of Using the Same BIOVEC TRANSFUSION, LLC (US) 2011-09-15 US disclosed
US-20110223662-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME BIOVEC TRANSFUSION, LLC (US) 2011-09-15 US disclosed
US-20110223663-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME BIOVEC TRANSFUSION, LLC (US) 2011-09-15 US disclosed
US-7964338-B2 Platelet preservation composition containing eptifibatide, a reversible factor IIa inhibitor and a hemoglobin oxygen carrier BIOVEC TRANSFUSION, LLC (US) 2011-06-21 US disclosed
US-20100221697-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING AND STORING THE SAME BioVec Transfusions, LLC (US) 2010-09-02 US disclosed
US-20090263781-A1 Composition for Preserving Platelets and Method of Using the Same BIOVEC, LLC. (US) 2009-10-22 US disclosed
US-20090253115-A1 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME BIOVEC, LLC. (US) 2009-10-08 US disclosed
US-20080233554-A1 antiplatelet agent, an anticoagulant, and an oxygen carrier, for maintaining freshness; may also contain an ultra-short acting broad spectrum anti-microbial agents BIOVEC, LLC (US) 2008-09-25 US disclosed
EP-1835803-A2 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME Biovec LLC (US) 2007-09-26 EP disclosed
US-20060177811-A1 Composition for preserving platelets and method of using the same BIOVEC TRANSFUSION, L.L.C. 2006-08-10 US disclosed
WO-2006076401-A2 COMPOSITION FOR PRESERVING PLATELETS AND METHOD OF USING THE SAME BIOVEC, LLC (US) 2006-07-20 WO disclosed