Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.42 |
| ▸ | CA2 | P00918 | 9/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958897 | 0.82 | ADK (0.39) | TSHRADKCA1CA2CA12 | |
| SCHEMBL263892 | 0.81 | ADORA1 (0.41) | — | |
| SCHEMBL15955793 | 0.75 | NPC1 (0.49) | TSHRADKCA1CA2NPC1 | |
| SCHEMBL4875722 | 0.75 | NPC1 (0.49) | TSHRADKCA1CA2NPC1 | |
| SCHEMBL4193972 | 0.71 | PYGL (0.50) | TSHR | |
| SCHEMBL6489385 | 0.71 | PYGL (0.50) | TSHR | |
| SCHEMBL11284980 | 0.71 | PYGL (0.50) | TSHR | |
| SCHEMBL7905414 | 0.71 | TSHR (0.59) | TSHRADKCA1CA2NPC1 | |
| SCHEMBL27135262 | 0.70 | TSHR (0.41) | TSHRADKCA1CA2NPC1 | |
| SCHEMBL319584 | 0.70 | TSHR (0.46) | TSHRADKCA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260541-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN OR PEPTIDE EXPRESSION | CureVac AG (DE) | 2017-12-27 | — | — | EP | disclosed |
| EP-2831241-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN OR PEPTIDE EXPRESSION | Curevac GmbH (DE) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013143699-A1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN OR PEPTIDE EXPRESSION | CUREVAC GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| US-20080085284-A1 | Nucleotide sequences for use in diagnosis, identification, typing/classification of mycobacterial virulence, infectivity and/or latency | PATELL VILLOO M | 2008-04-10 | — | — | US | disclosed |