Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579811 | 0.94 | KDM4E (0.36) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL21856613 | 0.90 | — | — | |
| Boric Acid SCHEMBL28579815 | 0.86 | KDM4E (0.36) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1892729 | 0.84 | KDM4E (0.37) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29475364 | 0.84 | KDM4E (0.37) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL22748788 | 0.82 | KDM4E (0.36) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29475366 | 0.82 | KDM4E (0.36) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6677429 | 0.80 | KDM4E (0.33) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5403801 | 0.79 | HDAC8 (0.41) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30254059 | 0.74 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896480-A1 | CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS | Bayer CropScience Aktiengesellschaft (DE) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006136309-A1 | CRIPOWELLINS AND SYNTHETIC DERIVATIVES THEREOF USED AS MEDICAMENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |