Sugi Predict

Sugi Predict / Compounds / SCHEMBL29475366

SCHEMBL29475366

SCHEMBL29475366

CC[n+]1ccccc1F.Cl[Sb-](Cl)(Cl)(Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.36
▸ NPC1 O15118 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ STAT3 P40763 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ POLB P06746 1/20 0.33
▸ TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22748788 1.00 KDM4E (0.36) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL21856613 0.92 — —
SCHEMBL29475364 0.86 KDM4E (0.37) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL1892729 0.86 KDM4E (0.37) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL28579811 0.84 KDM4E (0.36) KDM4ENPC1RAB9ASMN1; SMN2MEN1
Boric Acid SCHEMBL28579815 0.84 KDM4E (0.36) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL5063458 0.82 KDM4E (0.35) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL6677429 0.82 KDM4E (0.33) KDM4ENPC1RAB9ASMN1; SMN2MEN1
SCHEMBL29475405 0.76 HDAC8 (0.43) KDM4ENPC1RAB9ASMN1; SMN2MEN1
Iodide SCHEMBL476411 0.72 NPC1 (0.32) NPC1RAB9ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
US-20260118357-A1 TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2026-04-30 — — US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 — — US disclosed
US-12306180-B2 Tri-functional crosslinking reagents ETH ZURICH (CH) 2025-05-20 — — US disclosed
EP-3856164-B1 MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS ACHILLION PHARMACEUTICALS INC (US) 2024-08-07 — — EP disclosed
US-11807627-B2 Morphic forms of complement factor D inhibitors Achillon Pharmaceuticals, Inc. (US) 2023-11-07 — — US disclosed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 — — US disclosed
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 — — EP disclosed
CN-115884977-A Stereoselective preparation of selected purine phosphoramidates 阿堤亚制药公司 2023-03-31 — — CN disclosed
US-20220373541-A1 Tri-functional Crosslinking Reagents ETH ZURICH (CH) 2022-11-24 — — US disclosed
US-20220233673-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2022-07-28 — — US disclosed
US-11385225-B2 Tri-functional crosslinking reagents ETH ZURICH (CH) 2022-07-12 — — US disclosed
EP-3980057-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF Institut Curie (FR) 2022-04-13 — — EP disclosed
EP-3981772-A1 TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE Otsuka Pharmaceutical Co., Ltd. (JP) 2022-04-13 — — EP disclosed
WO-2022040473-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2022-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 KDM4E 2432/4885NPC1 4761/4885RAB9A 1465/4885
US-11385225-B2 Tri-functional crosslinking reagents ADGRF1, FCGR3B, FCGR2A KDM4E 4672/4885NPC1 4513/4885RAB9A 4742/4885
US-20220373541-A1 Tri-functional Crosslinking Reagents ADGRF1, SIGLEC7, ADGRE5 KDM4E 3999/4885NPC1 4640/4885RAB9A 4594/4885
US-11807627-B2 Morphic forms of complement factor D inhibitors CFD, CFH, CFB KDM4E 2408/4885NPC1 1227/4885RAB9A 1921/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 KDM4E 2972/4885NPC1 4724/4885RAB9A 1754/4885
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC KDM4E 3678/4885NPC1 1054/4885RAB9A 1398/4885
US-20260118357-A1 TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE BTD, FABP2, FABP3 KDM4E 3165/4885NPC1 3029/4885RAB9A 3319/4885
US-12306180-B2 Tri-functional crosslinking reagents ADGRF1, SIGLEC7, ADGRE5 KDM4E 3999/4885NPC1 4640/4885RAB9A 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.