Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.49 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.49 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | IGF2R | P11717 | 4/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059685 | 1.00 | FBP1 (0.58) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL31540137 | 0.98 | FBP1 (0.59) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL17581993 | 0.98 | FBP1 (0.59) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL23723111 | 0.98 | FBP1 (0.59) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL5063689 | 0.97 | FBP1 (0.54) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL5063695 | 0.97 | FBP1 (0.54) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL30748277 | 0.95 | FBP1 (0.56) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL3411522 | 0.95 | FBP1 (0.56) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| SCHEMBL1469765 | 0.95 | FBP1 (0.56) | FBP1P2RY14P2RY2P2RY4AMDHD2 | |
| Pyrophosphoric Acid SCHEMBL7455384 | 0.86 | FBP1 (0.72) | FBP1P2RY14P2RY2P2RY4AMDHD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193384-B2 | Synthesized using diphosphitylating reagents via solid-phase synthesis; antisense therapy; genetic disorders; anticarcinogenic agents, viricides | Board of Governors for Higher Education, State of Rhode Island and Providence Plantation (US) | 2012-06-05 | — | — | US | disclosed |
| US-20080207551-A1 | MODIFIED OLIGONUCLEOTIDES CONTAINING DIPHOSPHODIESTER INTERNUCLEOTIDE LINKAGES | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE (US) | 2008-08-28 | — | — | US | disclosed |