Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.72 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.59 |
| ▸ | IGF2R | P11717 | 4/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | UMPS | P11172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308485 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL16710620 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL5001024 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL4997000 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL187934 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL24450790 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL30471819 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL708955 | 0.94 | FBP1 (0.81) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL14901025 | 0.93 | FBP1 (0.78) | FBP1AMDHD2IGF2RP2RY14UMPS | |
| SCHEMBL4358029 | 0.93 | FBP1 (0.78) | FBP1AMDHD2IGF2RP2RY14UMPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023308-A4 | INHIBITORS OF NUCLEOSIDE METABOLISM | EINSTEIN COLL MED (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1023308-A1 | INHIBITORS OF NUCLEOSIDE METABOLISM | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019338-A1 | INHIBITORS OF NUCLEOSIDE METABOLISM | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-04-22 | — | — | WO | disclosed |
| EP-0260012-A1 | Promoter for expression of heterologous proteins in mammalian cells | MERCK & CO. INC. (US) | 1988-03-16 | — | — | EP | disclosed |