Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218875 | 1.00 | GRM2 (0.31) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL471787 | 0.98 | — | — | |
| Formic Acid SCHEMBL8030842 | 0.94 | GRM2 (0.32) | GRM2GRM3GRM4CYP1A2ALOX15 | |
| SCHEMBL5961836 | 0.93 | — | — | |
| SCHEMBL8876149 | 0.91 | — | — | |
| Lactic Acid SCHEMBL7559083 | 0.88 | TP53 (0.35) | — | |
| SCHEMBL7122613 | 0.88 | — | — | |
| SCHEMBL8103672 | 0.87 | GRM8 (0.31) | GRM2GRM3TDP1GRM8GRM6 | |
| SCHEMBL9094889 | 0.87 | — | — | |
| SCHEMBL7157746 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | claimed |
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080265206-A1 | Enzymatic conversion of 5-norbornene-2-carbonitrile to give 5-norbornene-2-carboxylic acid with a high substrate concentration; nucleic acid encoding said polypeptide; suitable for preparation of cyclic olefin copolymers, pharmaceutical intermediates, pesticides or fragrances | NT5E, NT5C2, CPN1 | GRM2 2332/4885GRM3 3240/4885GRM4 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.