SCHEMBL218875

SCHEMBL218875

O=C(O)C12C=CC(CC1)C2

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.31
GRM3 Q14832 2/20 0.31
GRM4 Q14833 2/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
LMNA P02545 1/20 0.31
GRM5 P41594 1/20 0.31
MTOR P42345 1/20 0.31
GRM1 Q13255 1/20 0.31
PLCB1 Q9NQ66 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5064896 1.00 GRM2 (0.31) GRM2GRM3GRM4CYP1A2ALOX15
Hydrochloric Acid SCHEMBL471787 0.98
Formic Acid SCHEMBL8030842 0.94 GRM2 (0.32) GRM2GRM3GRM4CYP1A2ALOX15
SCHEMBL5961836 0.93
SCHEMBL8876149 0.91
Lactic Acid SCHEMBL7559083 0.88 TP53 (0.35)
SCHEMBL7122613 0.88
SCHEMBL8103672 0.87 GRM8 (0.31) GRM2GRM3TDP1GRM8GRM6
SCHEMBL9094889 0.87
SCHEMBL7157746 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12544455-B2 Targeted poly(beta-amino ester)s IXAKA FRANCE (FR) 2026-02-10 US claimed
US-20250345456-A1 Targeted Poly(beta-amino ester)s IXAKA FRANCE (FR) 2025-11-13 US claimed
US-20250259837-A1 RESPONSIVE LAYER FOR PHOTOLITHOGRAPHY FILM STACK APPLIED MATERIALS, INC. 2025-08-14 US claimed
US-20250161536-A1 CLICK-CROSSLINKED HYDROGELS AND METHODS OF USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2025-05-22 US claimed
EP-4547291-A1 LIGHT BEAM PROJECTION GUIDED BIOFABRICATION OF ALIGNED TISSUES ETH Zurich (CH) 2025-05-07 EP claimed
CN-119930418-A Preparation method of norbornene carboxylic acid 滨州魏桥国科高等技术研究院 2025-05-06 CN claimed
CN-119789880-A Biological manufacture of directional tissue guided by beam projection 苏黎世联邦理工学院 2025-04-08 CN claimed
WO-2025021165-A1 POLYMER COMPRISING ESTER-IMIDE STRUCTURAL UNIT, AND PREPARATION METHOD THEREFOR 西湖大学 2025-01-30 WO claimed
CN-118684803-A Polydicyclopentadiene resin and preparation method thereof 四川大学 2024-09-24 CN claimed
US-12053561-B2 Click-crosslinked hydrogels and methods of use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-08-06 US claimed
US-6103445-A POLYMER OF A T-BUTYL ESTER OF NORBORNENE CARBOXYLIC ACID ANALOG, A PHOTOACID GENERATOR, AND PLASTICIZER COMPRISING A DI-TERT-BUTYL ESTER OF A POLYCYCLIC DICARBOXYLIC ACID; TRANSPARENCY AT 193 NM AND AN ETCH RESISTANCE; RESOLUTION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-08-15 US claimed
US-6048664-A Energy-sensitive resist material and a process for device fabrication using an energy-sensitive resist material LUCENT TECHNOLOGIES, INC. (US) 2000-04-11 US claimed
CN-1228410-A Copolymer resin, preparation thereof, and photo resist using the same HYUNDAI ELECTRONICS IND (KR) 1999-09-15 CN claimed
US-5717098-A GAMMA-LACTONE CHEMICAL INTERMEDIATE, USED TO PRODUCE A SINGLE ENANTIOMER OF AMINOAZANORADAMANTANE WHICH IS COUPLED TO AROMATIC ACID DERIVEATIVE TO PRODUCE A COMPOUND USEFUL AS 5-HT-AGONISTS OR ANTAGONSITS G. D. SEARLE & CO. (US) 1998-02-10 US claimed
CN-1164224-A Monomers and composition with can be crosslinked and crosslinked polymers CIBA GEIGY AG (CH) 1997-11-05 CN claimed
EP-0498618-B1 Stabilization of thiolene compositions LOCTITE CORP (US) 1995-04-26 EP claimed
WO-1993006171-A1 POLYMER BLENDS OF NORBORNENE DICARBOXIMIDES MONSANTO COMPANY (US) 1993-04-01 WO claimed
EP-0295076-B1 POLYOLEFINS INCORPORATING FUNCTIONAL GROUPS, MASKED FUNCTIONAL GROUP-CONTAINING MONOMERS, REACTION MIXTURES, AND METHODS FOR PREPARING SAME EXXON CHEMICAL PATENTS INC. (US) 1992-09-30 EP claimed
US-4987200-A METALLIZATION BEFORE POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-01-22 US claimed
EP-0295076-A1 Polyolefins incorporating functional groups, masked functional group-containing monomers, reaction mixtures, and methods for preparing same EXXON CHEMICAL PATENTS INC. (US) 1988-12-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544455-B2 Targeted poly(beta-amino ester)s DNER, POTEE, BCAT1 GRM2 4258/4885GRM3 3732/4885GRM4 4159/4885
US-20250345456-A1 Targeted Poly(beta-amino ester)s POTEE, BCAT1, EBPL GRM2 2896/4885GRM3 2068/4885GRM4 2190/4885
US-20250161536-A1 CLICK-CROSSLINKED HYDROGELS AND METHODS OF USE VCL, CD44, LOX GRM2 2990/4885GRM3 3023/4885GRM4 2780/4885
US-12053561-B2 Click-crosslinked hydrogels and methods of use VCL, CD44, LOX GRM2 2990/4885GRM3 3023/4885GRM4 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.