Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.73 |
| ▸ | HTR3B | O95264 | 3/20 | 0.73 |
| ▸ | HTR3A | P46098 | 3/20 | 0.73 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.73 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.73 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4795762 | 0.98 | HTR3E (0.71) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL538276 | 0.83 | HTR3E (0.96) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4797259 | 0.79 | GRIN2B (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5064966 | 0.79 | TAAR1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1230273 | 0.78 | NOS2 (0.67) | HTR3AGRIN2BGRIN1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL4799473 | 0.77 | TAAR1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4801101 | 0.76 | TAAR1 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL4003818 | 0.76 | NOS2 (0.64) | HTR3AGRIN2BGRIN1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL4800746 | 0.75 | GRIN2B (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL3396687 | 0.73 | IDO1 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656953-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-07 | — | — | US | disclosed |
| US-8642278-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-02-04 | — | — | US | disclosed |
| EP-1962892-A2 | INHIBITION OF CELL PROLIFERATION | University of South Florida (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20070254318-A1 | INHIBITION OF CELL PROLIFERATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-01 | — | — | US | disclosed |
| WO-2007062222-A2 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254318-A1 | INHIBITION OF CELL PROLIFERATION | RB1, RAF1, NRAS | HTR3E 3959/4885HTR3B 4128/4885HTR3A 4562/4885 |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | RB1, RAF1, NRAS | HTR3E 3959/4885HTR3B 4128/4885HTR3A 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.