SCHEMBL5065660

SCHEMBL5065660

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(=O)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.74
PPARG P37231 10/20 0.74
PPARD Q03181 2/20 0.74
ACE P12821 1/20 0.65
ITGB3 P05106 2/20 0.58
ITGA2B P08514 2/20 0.58
CTSS P25774 3/20 0.58
CTSK P43235 2/20 0.58
CTSL P07711 1/20 0.58
CTSB P07858 1/20 0.58
ITGB1 P05556 1/20 0.57
ITGAV P06756 1/20 0.57
ITGB5 P18084 1/20 0.57
PTPN1 P18031 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12984836 1.00 PPARA (0.74) PPARAPPARGPPARDACEITGB3
SCHEMBL9005835 1.00 PPARA (0.74) PPARAPPARGPPARDACEITGB3
SCHEMBL2296993 0.94 PPARA (0.67) PPARAPPARGPPARDACEITGB3
SCHEMBL10622577 0.90 PPARG (0.65) PPARAPPARGPPARDACEITGB3
SCHEMBL66220 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3
SCHEMBL67020 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3
SCHEMBL27909397 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3
SCHEMBL606309 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3
SCHEMBL21473784 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3
SCHEMBL795685 0.89 ACE (0.79) PPARAPPARGPPARDACEITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
CN-118843479-A Boronated dipeptide amino acid compositions and methods for boron neutron capture therapy TAE生命科学有限责任公司 2024-10-25 CN disclosed
EP-4408471-A2 BORYLATED DI-PEPTIDE AMINO ACID COMPOSITIONS FOR USE IN BORON NEUTRON CAPTURE THERAPY AND METHODS THEREOF Tae Life Sciences (US) 2024-08-07 EP disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 US disclosed
US-20240057599-A1 METHODS FOR IMPROVING FRUIT QUALITY THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2024-02-22 US disclosed
US-20240049709-A1 METHOD OF CONTROLLING FUNGAL INFECTIONS IN PLANTS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O), THE VOLCANI INSTITUTE (IL) 2024-02-15 US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 US disclosed
US-6423689-B1 Peptidyl calcium channel blockers WARNER-LAMBERT COMPANY 2002-07-23 US disclosed
US-6410585-B1 THERAPY FOR NON-INSULIN DEPEND DIABETES BIOVITRUM AB (SE) 2002-06-25 US disclosed
US-20020035137-A1 Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors ABBOTT LABORATORIES 2002-03-21 US disclosed
WO-2002018323-A2 AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS ABBOTT LABORATORIES (US) 2002-03-07 WO disclosed
US-6353023-B1 AROMATIC COMPOUNDS WITH AMIDE GROUPS PHARMACIA & UPJOHN COMPANY 2002-03-05 US disclosed
EP-1019364-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 2000-07-19 EP disclosed
WO-1999011606-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PHARMACIA & UPJOHN COMPANY (US) 1999-03-11 WO disclosed
US-5578601-A Nonpeptide bradykinin antagonists STERLING WINTHROP INC. (US) 1996-11-26 US disclosed
US-5510380-A TREATING INFLAMMATORY CONDITIONS STERLING WINTHROP, INC. (US) 1996-04-23 US disclosed
US-4762881-A Photoreactive benzoylphenylalanines and related peptides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH PPARA 4497/4885PPARG 4002/4885PPARD 4603/4885
US-20020035137-A1 Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors PPM1A, PTPRO, PTP4A1 PPARA 2457/4885PPARG 1733/4885PPARD 3392/4885
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 PPARA 4384/4885PPARG 2882/4885PPARD 4423/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 PPARA 3778/4885PPARG 3003/4885PPARD 3999/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH PPARA 4497/4885PPARG 4002/4885PPARD 4603/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH PPARA 4462/4885PPARG 4013/4885PPARD 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.