Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002006 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL5068813 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL5071346 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL25261946 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL18554279 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL25258303 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL29273270 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL20973270 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM | |
| SCHEMBL6002159 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM | |
| SCHEMBL5065994 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1659121-A1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | AVPR1B, AVPR1A, AVPR2 | DPP4 2704/4885DPP8 2961/4885DPP9 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.