Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 6/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498387 | 1.00 | ATM (0.50) | ATMPIK3CDALDH1A1MMEAVPR2 | |
| SCHEMBL5068787 | 1.00 | ATM (0.50) | ATMPIK3CDALDH1A1MMEAVPR2 | |
| SCHEMBL20973270 | 1.00 | ATM (0.50) | ATMPIK3CDALDH1A1MMEAVPR2 | |
| SCHEMBL5065994 | 1.00 | ATM (0.50) | ATMPIK3CDALDH1A1MMEAVPR2 | |
| SCHEMBL7957159 | 0.84 | MMP2 (0.44) | ATM | |
| SCHEMBL3891979 | 0.83 | ATM (0.45) | ATMPIK3CDALDH1A1 | |
| SCHEMBL2645663 | 0.83 | ATM (0.45) | ATMPIK3CDALDH1A1 | |
| SCHEMBL6002006 | 0.80 | DPP4 (0.34) | ATMDPP4DPP8DPP9 | |
| SCHEMBL8529323 | 0.80 | ATM (0.30) | ATM | |
| SCHEMBL5068813 | 0.80 | DPP4 (0.34) | ATMDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659121-A1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-05-24 | — | — | EP | disclosed |