Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068813 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL5065875 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL5071346 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL25261946 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL18554279 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL25258303 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL29273270 | 0.83 | PEPD (0.35) | DPP4DPP8DPP9PEPDXPNPEP1 | |
| SCHEMBL20973270 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM | |
| SCHEMBL6002159 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM | |
| SCHEMBL5065994 | 0.80 | ATM (0.50) | DPP4DPP8DPP9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659121-A1 | 1,3-DIHYDRO-2H-INDOL-2-ONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-05-24 | — | — | EP | disclosed |