Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.42 |
| ▸ | GNPAT | O15228 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279118 | 0.88 | CTSK (0.50) | NOD1ALDH1A1CTSKMEN1GAA | |
| SCHEMBL2074961 | 0.88 | CTSK (0.50) | NOD1ALDH1A1CTSKMEN1GAA | |
| SCHEMBL17637824 | 0.88 | MAPT (0.46) | FOLH1GNPATSMN1; SMN2KDM4EMAPT | |
| SCHEMBL29400699 | 0.88 | MAPT (0.46) | FOLH1GNPATSMN1; SMN2KDM4EMAPT | |
| SCHEMBL19365108 | 0.88 | MAPT (0.46) | FOLH1GNPATSMN1; SMN2KDM4EMAPT | |
| SCHEMBL8360180 | 0.85 | MEN1 (0.40) | FOLH1NOD1ALDH1A1CTSKMEN1 | |
| SCHEMBL5057123 | 0.85 | KMT2A (0.51) | NOD1SMN1; SMN2CHRM2CHRM4CHRM1 | |
| SCHEMBL557473 | 0.82 | NOD1 (0.56) | FOLH1NOD1GNPATKMT2ASLC6A5 | |
| SCHEMBL29354600 | 0.82 | GNPAT (0.45) | FOLH1GNPATSMN1; SMN2KDM4EMAPT | |
| SCHEMBL17600320 | 0.82 | CTSK (0.52) | ALDH1A1CTSKMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004290-A1 | Anti-Cancer Agents | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-01-03 | — | — | US | disclosed |
| EP-1694640-A4 | ANTI-CANCER AGENTS | UNIV QUEENSLAND (AU) | 2007-01-10 | — | — | EP | disclosed |
| EP-1694640-A1 | ANTI-CANCER AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005051901-A1 | ANTI-CANCER AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004290-A1 | Anti-Cancer Agents | TP53, TOP2A, MCL1 | FOLH1 170/4885NOD1 4553/4885GNPAT 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.