⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252 | 0.79 | — | — | |
| SCHEMBL7042181 | 0.78 | NFE2L2 (0.53) | — | |
| SCHEMBL7042184 | 0.78 | NFE2L2 (0.53) | — | |
| SCHEMBL5022136 | 0.77 | — | — | |
| SCHEMBL27622085 | 0.77 | MAPT (0.55) | — | |
| SCHEMBL18611 | 0.74 | LRRK2 (0.46) | — | |
| SCHEMBL29533314 | 0.74 | LRRK2 (0.46) | — | |
| SCHEMBL2659230 | 0.74 | ALOX5AP (0.39) | — | |
| SCHEMBL2651801 | 0.74 | CYP11B2 (0.37) | — | |
| SCHEMBL18827520 | 0.74 | GRM5 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 665 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-221558702-U | Centrifugal separation device for preparing 2-cyano-3-fluoropyridine | 山东佰隆医药有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-117199519-A | Electrolyte, preparation method and application thereof, and lithium battery | 北京纳米能源与系统研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-116924979-A | Preparation method of 2-cyano-3-fluoropyridine | 阜新金特莱氟化学有限责任公司 | 2023-10-24 | — | — | CN | claimed |
| CN-111244543-A | High-voltage lithium ion battery electrolyte additive, electrolyte, battery and formation method thereof | 松山湖材料实验室 | 2020-06-05 | — | — | CN | claimed |
| CN-104387369-A | Synthesis method and application of thermal activation delayed fluorescence material | NANJING UNIVERSITY OF TECHNOLOGY | 2015-03-04 | — | — | CN | claimed |
| US-8541580-B2 | Process for the preparation of pyrazinone thrombin inhibitor and its intermediates | DIAKRON PHARMACEUTICALS, INC. (US) | 2013-09-24 | — | — | US | claimed |
| EP-2496087-A1 | PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES | Diakron Pharmaceuticals, Inc. (US) | 2012-09-12 | — | — | EP | claimed |
| WO-2011056806-A1 | PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES | DIAKRON PHARMACEUTICALS, INC. (US) | 2011-05-12 | — | — | WO | claimed |
| US-20110105753-A1 | PROCESS FOR THE PREPARATION OF PYRAZINONE THROMBIN INHIBITOR AND ITS INTERMEDIATES | DIAKRON PHARMACEUTICALS, INC. (US) | 2011-05-05 | — | — | US | claimed |
| EP-1341784-A2 | PROCESS FOR MAKING A THROMBIN INHIBITOR | Merck & Co., Inc. (US) | 2003-09-10 | — | — | EP | claimed |
| US-20020103379-A1 | Process for making a thrombin inhibitor | MERCK SHARP & DOHME LTD. (GB) | 2002-08-01 | — | — | US | claimed |
| WO-2002046160-A2 | PROCESS FOR MAKING A THROMBIN INHIBITOR | MERCK & CO., INC. (US) | 2002-06-13 | — | — | WO | claimed |
| EP-4590675-B1 | HETEROCYCLIC SIK INHIBITORS | PFIZER (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-3364967-B1 | FERROPORTIN INHIBITORS | VIFOR INT AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| EP-4105216-B1 | DIHYDRONAPHTHYRIDINONE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | GENFLEET THERAPEUTICS SHANGHAI INC (CN) | 2026-05-20 | — | — | EP | disclosed |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | disclosed |
| WO-2000074682-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000075134-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000058302-A1 | DIHYDROPYRIMIDINES AND THEIR USE IN THE TREATMENT OF HEPATITIS B | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| EP-1034783-A1 | AMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |