SCHEMBL5067052

SCHEMBL5067052

O=C(COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H](CO)OP(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.36
TPI1 P60174 2/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803701 0.84 CYP2C9 (0.44) PGDPTPN1
SCHEMBL24438 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL9737043 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL4136973 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL9738422 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL19512307 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL851610 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL16322088 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL8472515 0.81 PGD (0.43) PGDTPI1PGK1PGK2
SCHEMBL4131096 0.81 PGD (0.43) PGDTPI1PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080268287-A1 Method of Converting Water-Soluble Active Proteins Into Hydrophobic Active Proteins, the Use of the Same for the Preparation of Monomolecular Layers of Oriented Active Proteins, and Devices Comprising the Same PROTEOGEN BIO S.R.L. (IT) 2008-10-30 US disclosed
EP-1951869-A1 METHOD OF CONVERTING WATER-SOLUBLE ACTIVE PROTEINS INTO HYDROPHOBIC ACTIVE PROTEINS, THE USE OF THE SAME FOR THE PREPARATION OF MONOMOLECULAR LAYERS OF ORIENTED ACTIVE PROTEINS, AND DEVICES COMPRISING THE SAME Proteogen Bio S.R.L. (IT) 2008-08-06 EP disclosed
WO-2007054839-A1 METHOD OF CONVERTING WATER-SOLUBLE ACTIVE PROTEINS INTO HYDROPHOBIC ACTIVE PROTEINS, THE USE OF THE SAME FOR THE PREPARATION OF MONOMOLECULAR LAYERS OF ORIENTED ACTIVE PROTEINS, AND DEVICES COMPRISING THE SAME PROTEOGEN BIO S.R.L. (IT) 2007-05-18 WO disclosed