Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARS1 | P54136 | 1/20 | 0.78 |
| ▸ | QARS1 | P47897 | 1/20 | 0.75 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.71 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.71 |
| ▸ | SRC | P12931 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.71 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.71 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.71 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.68 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.68 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.68 |
| ▸ | LDHA | P00338 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063172 | 0.89 | P2RY1 (0.71) | RARS1QARS1P2RY1P2RY2SRC | |
| SCHEMBL3046222 | 0.87 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL5055892 | 0.87 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Adenosine Phosphate SCHEMBL15670721 | 0.86 | P2RY1 (0.77) | QARS1P2RY1P2RY2SRCSMN1; SMN2 | |
| Adenosine Phosphate SCHEMBL7225652 | 0.86 | P2RY1 (0.77) | QARS1P2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL10980597 | 0.84 | P2RY1 (0.77) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL28319431 | 0.84 | P2RY1 (0.82) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Diadenosine Tetraphosphate SCHEMBL4069414 | 0.83 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL21067711 | 0.83 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| Diadenosine Tetraphosphate SCHEMBL4363130 | 0.83 | P2RY1 (1.00) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318884-A1 | Methods for Altering Gene Expression and Methods of Treatment Utilizing Same | THE UAB RESEARCH FOUNDATION (US) | 2008-12-25 | — | — | US | disclosed |
| WO-2006105038-A2 | METHODS OF ALTERING GENE EXPRESSION AND METHODS OF TREATMENT UTILIZING SAME | THE UAB RESEARCH FOUNDATION (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20040214255-A1 | Identifying modulators of glucose transport for use in treatment of pancreatic and nervous system disorders | MYRIAD GENETICS, INCORPORATED | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318884-A1 | Methods for Altering Gene Expression and Methods of Treatment Utilizing Same | TRDMT1, TARBP1, TRMT1 | RARS1 26/4885QARS1 34/4885P2RY1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.