Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.95 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.95 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.56 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13897852 | 1.00 | GPR84 (0.95) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL44151 | 1.00 | GPR84 (0.95) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL337352 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4757199 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525377 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2933185 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525619 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL22842 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2709599 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525700 | 0.98 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6165695-A | — | — | None | — | — | JP | disclosed |
| US-11208435-B2 | Verticilide enantiomer and methods of inhibiting cardiac ryanodine receptor-mediated intracellular calcium release | VANDERBILT UNIVERSITY (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200262872-A1 | VERTICILIDE ENANTIOMER AND METHODS OF INHIBITING CARDIAC RYANODINE RECEPTOR-MEDIATED INTRACELLULAR CALCIUM RELEASE | VANDERBILT UNIVERSITY | 2020-08-20 | — | — | US | disclosed |
| CN-104540845-B | Novel cyclic depsipeptide derivative and pest control agent containing same | 明治制果药业株式会社 | 2018-01-26 | — | — | CN | disclosed |
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENT -RUN FÜR GESUNDHEIT UND (DE) | 2015-02-05 | — | — | US | disclosed |
| EP-2736331-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013014245-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2013-01-31 | — | — | WO | disclosed |
| US-20080261286-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20050202545-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-0920852-B1 | Keratin fiber strengthening agent and method for strengthening keratin fiber | TAKASAGO PERFUMERY CO LTD (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-6379659-B1 | APPLYING (2S,3R)-2-ACYLAMINOALKANE-1,3-DIOL TO FIBER | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-0920852-A2 | Keratin fiber strengthening agent and method for strengthening keratin fiber | Takasago International Corporation (JP) | 1999-06-09 | — | — | EP | disclosed |
| JP-H06165695-A | PRODUCTION OF OPTICALLY ACTIVE 2-HYDROXYARYLACETIC ACID AND ITS DERIVATIVE | SHOWA DENKO KK | 1994-06-14 | — | — | JP | disclosed |
| US-4307112-A | 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208435-B2 | Verticilide enantiomer and methods of inhibiting cardiac ryanodine receptor-mediated intracellular calcium release | RYR2, RYR1, ATP2A1 | GPR84 320/4885FFAR1 168/4885MAPT 3465/4885 |
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HAO1, HAAO, HAO2 | GPR84 2235/4885FFAR1 197/4885MAPT 3568/4885 |
| US-20200262872-A1 | VERTICILIDE ENANTIOMER AND METHODS OF INHIBITING CARDIAC RYANODINE RECEPTOR-MEDIATED INTRACELLULAR CALCIUM RELEASE | RYR2, RYR1, ATP2A1 | GPR84 320/4885FFAR1 168/4885MAPT 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.