⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367098 | 0.92 | FAAH (0.73) | — | |
| SCHEMBL6899719 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL28767487 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL29287856 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL3950801 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL5126810 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL8458168 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL6344027 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL609881 | 0.90 | FAAH (0.77) | — | |
| SCHEMBL5083248 | 0.90 | FAAH (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322184-B1 | N-(2-ALKYL-3-MERCAPTO-1,5-DI-OXOALKYL)GLYCINAMIDE DERIVATIVES AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1992-12-02 | — | — | EP | claimed |
| WO-2024102633-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20200248041-A1 | ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT | SIKA TECHNOLOGY AG (CH) | 2020-08-06 | — | — | US | disclosed |
| EP-3688052-A1 | ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT | Sika Technology AG (CH) | 2020-08-05 | — | — | EP | disclosed |
| US-10428108-B2 | Difluoroketamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2019-10-01 | — | — | US | disclosed |
| CN-107814938-A | The preparation method of fluorine silicon nonionic surfactant | 九江学院 | 2018-03-20 | — | — | CN | disclosed |
| US-20180057526-A1 | NEW DIFLUOROKETAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2018-03-01 | — | — | US | disclosed |
| CN-104817472-A | Novel gossypol derivatives, and preparation method and antineoplastic application thereof | UNIV WUHAN | 2015-08-05 | — | — | CN | disclosed |
| CN-103917578-A | Bulk hydrophilic funtionalization of polyamide 46 | ENCUBATOR AB | 2014-07-09 | — | — | CN | disclosed |
| CN-102414241-A | Microencapsulated composition containing imidazole compound, curable composition using same, and masterbatch-type curing agent | ASAHI KASEI E MATERIALS CORP | 2012-04-11 | — | — | CN | disclosed |
| US-7884199-B2 | computer aided drug design; pharmacogenetics around telaprevir resistance; hepatitis C virus (HCV) | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-02-08 | — | — | US | disclosed |
| US-20090191555-A1 | HCV NS3-NS4 Protease Resistance Mutants | VERTEX PHARMACEUTICALS (US) | 2009-07-30 | — | — | US | disclosed |
| US-20080261286-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-10-23 | — | — | US | disclosed |
| US-20050202545-A1 | Methods for producing optically active alpha-hydroxy amides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-15 | — | — | US | disclosed |
| CN-1180478-A | Butachlor-oxidiazon emulsifiable concentrate and preparation technique | NANTONG CITY PLANT PROTECTION (CN) | 1998-05-06 | — | — | CN | disclosed |
| EP-0440506-B1 | Derivatized ethylene alpha-olefin polymer useful as multifunctional viscosity index improver | EXXON CHEMICAL PATENTS INC (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0440506-A2 | Derivatized ethylene alpha-olefin polymer useful as multifunctional viscosity index improver | EXXON CHEMICAL PATENTS INC. (US) | 1991-08-07 | — | — | EP | disclosed |