Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.36 |
| ▸ | CETP | P11597 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587621 | 0.87 | CETP (0.36) | TACR1CETPSLC6A4SLC6A2 | |
| SCHEMBL5067467 | 0.86 | TACR1 (0.40) | TACR1CETPSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5067462 | 0.84 | TACR1 (0.37) | TACR1CETPSLC6A4 | |
| SCHEMBL1588631 | 0.80 | CETP (0.51) | CETP | |
| SCHEMBL1587799 | 0.79 | CETP (0.51) | CETP | |
| SCHEMBL1587626 | 0.79 | CETP (0.41) | CETP | |
| SCHEMBL1588007 | 0.79 | CETP (0.47) | CETP | |
| SCHEMBL1587796 | 0.78 | CETP (0.47) | CETP | |
| SCHEMBL5072379 | 0.77 | TACR1 (0.43) | TACR1 | |
| SCHEMBL1587680 | 0.74 | CETP (0.44) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |