Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587620 | 0.88 | MGLL (0.38) | TACR1MGLLSLC6A4CETP | |
| SCHEMBL5067467 | 0.85 | TACR1 (0.40) | TACR1SLC6A4CETP | |
| SCHEMBL5067463 | 0.84 | TACR1 (0.36) | TACR1SLC6A4CETP | |
| SCHEMBL1587625 | 0.82 | MGLL (0.41) | MGLLCETP | |
| SCHEMBL1588629 | 0.81 | CETP (0.48) | MGLLCETP | |
| SCHEMBL1588002 | 0.81 | CETP (0.45) | MGLLCETP | |
| SCHEMBL1587797 | 0.80 | CETP (0.42) | MGLLCETP | |
| SCHEMBL1587794 | 0.79 | CETP (0.38) | MGLLCETP | |
| SCHEMBL1588012 | 0.77 | CETP (0.41) | MGLLCETP | |
| SCHEMBL5072379 | 0.76 | TACR1 (0.43) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |