Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 0.58 |
| ▸ | MMP2 | P08253 | 10/20 | 0.58 |
| ▸ | MMP8 | P22894 | 9/20 | 0.58 |
| ▸ | MMP10 | P09238 | 9/20 | 0.58 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067851 | 1.00 | MMP13 (0.58) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL688588 | 0.86 | MMP13 (0.62) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL688587 | 0.86 | MMP13 (0.62) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL689440 | 0.80 | MMP13 (0.72) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL689439 | 0.80 | MMP13 (0.72) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL689478 | 0.79 | MMP2 (0.72) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL4934733 | 0.77 | MMP13 (0.72) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL4373943 | 0.77 | MMP13 (0.79) | MMP13MMP2MMP8MMP10 | |
| SCHEMBL689613 | 0.75 | MMP13 (0.63) | MMP13MMP2MMP8MMP10MMP3 | |
| SCHEMBL10290012 | 0.75 | MMP13 (0.76) | MMP13MMP2MMP8MMP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-A1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-08-06 | — | — | EP | disclosed |