Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551725 | 0.95 | CCR5 (0.34) | CCR5 | |
| SCHEMBL5661908 | 0.71 | — | — | |
| SCHEMBL28477067 | 0.71 | CCR5 (0.48) | CCR5FAAHTRPV1 | |
| SCHEMBL11292742 | 0.66 | CCR5 (0.40) | CCR5 | |
| SCHEMBL27496081 | 0.62 | — | — | |
| SCHEMBL819092 | 0.62 | FAAH (0.68) | FAAHTRPV1 | |
| SCHEMBL29274398 | 0.62 | FAAH (0.68) | FAAHTRPV1 | |
| SCHEMBL1324284 | 0.62 | FAAH (0.68) | FAAHTRPV1 | |
| SCHEMBL506356 | 0.62 | FAAH (0.68) | FAAHTRPV1 | |
| SCHEMBL24218814 | 0.60 | FAAH (0.74) | FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545923-A1 | Antibacterial agents | Alchemia Limited (AU) | 2013-01-16 | — | — | EP | disclosed |
| EP-1934388-B1 | METHOD OF DRUG DESIGN | ALCHEMIA LTD (AU) | 2012-12-05 | — | — | EP | disclosed |
| EP-1962864-A1 | ANTIBACTERIAL AGENTS | Alchemia Limited (AU) | 2008-09-03 | — | — | EP | disclosed |
| EP-1934388-A1 | METHOD OF DRUG DESIGN | Alchemia Ltd (AU) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007070947-A1 | ANTIBACTERIAL AGENTS | ALCHEMIA LTD (AU) | 2007-06-28 | — | — | WO | disclosed |
| EP-1797428-A1 | SELECTIVE INHIBITORS | Alchemia Pty Ltd (AU) | 2007-06-20 | — | — | EP | disclosed |
| WO-2007038829-A1 | METHOD OF DRUG DESIGN | ALCHEMIA LTD (AU) | 2007-04-12 | — | — | WO | disclosed |
| WO-2006037159-A1 | SELECTIVE INHIBITORS | ALCHEMIA LIMITED (AU) | 2006-04-13 | — | — | WO | disclosed |