SCHEMBL506796

SCHEMBL506796

OCc1sccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7380102 0.81
SCHEMBL10947172 0.77
SCHEMBL16670518 0.75
SCHEMBL266174 0.75
SCHEMBL6999271 0.75
SCHEMBL31612604 0.74 ADRA1D (0.37)
SCHEMBL25239748 0.73 ADRA1D (0.36)
SCHEMBL7961734 0.73 ADAMTS5 (0.40)
SCHEMBL11725099 0.73 ADRA1D (0.39)
SCHEMBL20678310 0.72 ADRA1D (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097104-A1 THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER PGI DRUG DISCOVERY LLC (US) 2025-05-08 WO disclosed
WO-2025049326-A1 TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 BIOCRYST PHARMACEUTICALS, INC. (US) 2025-03-06 WO disclosed
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-11778893-B2 Indaceno derivatives as organic semiconductors CLAP CO., LTD. (KR) 2023-10-03 US disclosed
US-11667630-B2 Nitrogen-containing 6-membered cyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2023-06-06 US disclosed
US-11667630-B2 Nitrogen-containing 6-membered cyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2023-06-06 US disclosed
US-11667630-B2 Nitrogen-containing 6-membered cyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2023-06-06 US disclosed
CN-111511736-B Nitrogen-containing 6-membered ring compound 旭化成制药株式会社 2023-03-24 CN disclosed
EP-3733665-B1 2-OXO-1,3,4-THIADIAZINAN-3-YL MOIETY CONTAINING COMPOUNDS WITH EP4 RECEPTOR AGONIST ACTIVITY ASAHI KASEI PHARMA CORP (JP) 2022-09-28 EP disclosed
WO-2000015634-A2 HIV PROTEASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2000-03-23 WO disclosed
US-6040328-A ANTIOXIDANT AGENTS HAVING CYTOPROTECTING ACTIVITY, AND WATER SOLUBLE OXIS INTERNATIONAL S.A. (US) 2000-03-21 US disclosed
US-5973009-A ANTIOXIDANT AND CYTOPROTECTING ACTIVITY OXIS INTERNATIONAL S.A. (US) 1999-10-26 US disclosed
EP-0948500-A1 CYCLIC ORGANOSELENIUM COMPOUNDS, THEIR PREPARATION AND THEIR USES OXIS Isle of Man, Limited (GB) 1999-10-13 EP disclosed
WO-1999006410-A1 HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS AMGEN INC. (US) 1999-02-11 WO disclosed
WO-1998029417-A1 CYCLIC ORGANOSELENIUM COMPOUNDS, THEIR PREPARATION AND THEIR USES OXIS ISLE OF MAN, LIMITED (GB) 1998-07-09 WO disclosed
EP-0850924-A1 Aromatic diselenides and selenosulphides for use as antioxidant agents OXIS Isle of Man, Limited (GB) 1998-07-01 EP disclosed
EP-0413293-A2 1-(Benzo[b]thienyl)-2-(thienyl) ethenes and related compounds, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-02-20 EP disclosed
US-4904674-A FREE OF AGGLOMERATION OF FIBRILLATION HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-02-27 US disclosed
US-4560701-A ANTIINFLAMMATORY, ANALGESIC AGENTS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1985-12-24 US disclosed