Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 19/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068165 | 1.00 | ITGB1 (0.53) | ITGB1ITGA4HDAC1 | |
| SCHEMBL5070339 | 0.91 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL5070343 | 0.91 | ITGB1 (0.59) | ITGB1ITGA4 | |
| SCHEMBL5070341 | 0.91 | ITGB1 (0.53) | ITGB1ITGA4HDAC1 | |
| SCHEMBL5068497 | 0.80 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL5068500 | 0.80 | ITGB1 (0.67) | ITGB1ITGA4 | |
| SCHEMBL5068354 | 0.78 | ITGB1 (0.81) | ITGB1ITGA4 | |
| SCHEMBL5066849 | 0.78 | ITGB1 (0.81) | ITGB1ITGA4 | |
| SCHEMBL5066844 | 0.78 | ITGB1 (0.81) | ITGB1ITGA4 | |
| SCHEMBL5066822 | 0.76 | ITGB1 (0.84) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234301-A1 | Alpha-4 Integrin Mediated Cell Adhesion Inhibitors for the Treatment or Prevention of Inflammatory Diseases | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234301-A1 | Alpha-4 Integrin Mediated Cell Adhesion Inhibitors for the Treatment or Prevention of Inflammatory Diseases | ITGB4, ITGA4, ICAM1 | ITGB1 5/4885ITGA4 2/4885HDAC1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.