Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.42 |
| ▸ | CA2 | P00918 | 10/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068280 | 1.00 | MEN1 (0.49) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL5068283 | 1.00 | MEN1 (0.49) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3178783 | 0.96 | MEN1 (0.54) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3178780 | 0.96 | MEN1 (0.54) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3178776 | 0.96 | MEN1 (0.54) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4852002 | 0.91 | MEN1 (0.46) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4852013 | 0.91 | MEN1 (0.46) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4852021 | 0.91 | MEN1 (0.46) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4785511 | 0.86 | CTSK (0.43) | — | |
| SCHEMBL6333387 | 0.85 | KDM4E (0.38) | MEN1KMT2AGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | BAYER HEALTHCARE AG (DE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | AADAC, AAAS, NOD2 | MEN1 1894/4885KMT2A 3331/4885GAA 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.