Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159541 | 0.80 | HPGD (0.55) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL25938096 | 0.79 | ALOX15 (0.57) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL5068292 | 0.78 | NPC1 (0.51) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL17661735 | 0.77 | ALOX15 (0.47) | ALDH1A1L3MBTL1LMNAMAPTALOX15 | |
| SCHEMBL1981436 | 0.77 | BCHE (0.58) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4916070 | 0.76 | ACKR3 (0.51) | RAB9ABCHEHDAC3HDAC4HDAC1 | |
| SCHEMBL8373326 | 0.76 | HDAC3 (0.45) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL6643291 | 0.75 | NPC1 (0.67) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL6226886 | 0.75 | NPC1 (0.51) | ALDH1A1L3MBTL1LMNANPC1RAB9A | |
| SCHEMBL3255804 | 0.75 | BCHE (0.50) | ALDH1A1L3MBTL1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| US-6534530-B1 | Administering (benzo)thiazole peptidomimetic as viricide; protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | DPP4, DPP3, DPP7 | ALDH1A1 2457/4885L3MBTL1 1728/4885LMNA 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.