Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 9/20 | 0.56 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.40 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136396 | 0.77 | KAT2B (0.57) | KAT2BGUCY1A1GUCY1B1HDAC6 | |
| SCHEMBL5068531 | 0.75 | KAT2B (0.56) | KAT2BGUCY1A1GUCY1B1HDAC6 | |
| SCHEMBL7137884 | 0.73 | HDAC6 (0.65) | KAT2BHDAC6 | |
| SCHEMBL10126543 | 0.73 | KAT2B (0.54) | KAT2BGUCY1A1GUCY1B1HDAC6 | |
| SCHEMBL14981759 | 0.73 | KAT2B (0.97) | KAT2B | |
| SCHEMBL4201098 | 0.73 | RAB9A (0.49) | HDAC6 | |
| SCHEMBL2611834 | 0.72 | KAT2B (0.52) | KAT2BGUCY1A1GUCY1B1HDAC6 | |
| SCHEMBL27729887 | 0.72 | MEN1 (0.46) | HDAC6 | |
| Hydrochloric Acid SCHEMBL513348 | 0.72 | KAT2B (1.00) | KAT2B | |
| SCHEMBL29416813 | 0.70 | KAT2B (1.00) | KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753723-B1 | SUBSTITUTED QUINOLINE DERIVATIVES AS MITOTIC KINESIN INHIBITORS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2008-08-13 | — | — | EP | claimed |